Brown Ditch US 421 Bridge (White County, Indiana)
Built 1929; rehabilitated 1960Concrete arch bridge over Brown Ditch on US 421Open to traffic
Cape Fear Memorial Bridge (New Hanover County, North Carolina)
Built 1969Vertical lift bridge over Cape Fear River on US 76/421 in WilmingtonOpen to traffic
Clay's Ferry Bridge (Fayette County, Kentucky)
Built 1946 as part of US 25; twin span added 1963 as part
of I-75; both spans widened in 1998 to form a single six-lane bridgeDeck truss bridge over the Kentucky River on I-75/US 25/US 421 at Clay's Ferry south of Lexington in LexingtonOpen to six lanes of traffic
Cripe Run US 421 Bridge (Clinton County, Indiana)
Built 1931Concrete arch bridge over Cripe Run on US 421Open to traffic
Finley Creek US 421 Bridge (Boone County, Indiana)
Built 1931; rehabilitated 1986Concrete arch bridge over Finley Creek on US 421Open to traffic
Hoagland Ditch US 421 Bridge (White County, Indiana)
Built 1929; rehabilitated 1960Concrete arch bridge over Hoagland Ditch on US 421Open to traffic
Kilmore Creek US 421 Bridge (Clinton County, Indiana)
Built 1940; rehabilitated 1985Pony truss bridge over Kilmore Creek on US 421Open to two-lane traffic
Madison-Milton Bridge (Jefferson County, Indiana)
Built 1928-29; rehabilitated 1997Cantilevered through truss bridge over Ohio River on US 421 between Madison, IN, and Milton, KYOpen to traffic
Muscatatuck River US 421 Bridge (Decatur County, Indiana)
Built 1929; rehabilitated 1961Concrete arch bridge over V Fork Muscatatuck River on US 421Open to traffic
South Fork US 421 Bridge (Clinton County, Indiana)
Built 1940; rehabilitated 1985Pony truss bridge over South Fork Wildcat Creek on US 421Open to traffic